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Job Description

About the role

The Manufacturing Night Shift Manager leads and supervises night‑shift manufacturing operations to ensure production goals and project deadlines are met safely, efficiently, and in full compliance with current Good Manufacturing Practices (cGMP), Environmental Health & Safety (EHS) requirements, and applicable regulations. This role plays a critical part in enabling reliable, high‑quality manufacturing outcomes that support Takeda’s mission to deliver life‑changing therapies to patients.

Site operations include aseptic filling, inspection, and packaging. The Manager is accountable for driving results aligned with plant strategic priorities while fostering a culture of safety, quality, compliance, and continuous improvement. As a people leader, this role sets the standard for Takeda values, coaching and developing teams to deliver strong performance and model decision‑making grounded in Patient, Trust, Reputation, and Business (PTRB) principles.

How you will contribute

• Lead and oversee night‑shift manufacturing activities to meet safety, quality, delivery, and cost objectives

• Allocate and manage resources across Filling, Inspection, and Packaging to ensure continuous value‑chain flow and achievement of production targets

• Drive timely issue escalation and coordinate cross‑functional actions to minimize delays and maintain production schedules

• Lead or support large‑scale operational initiatives such as shutdowns, startups, and new process or facility implementations

• Champion DMAIC and continuous improvement methodologies to address issues impacting safety, quality, yield, or throughput

• Ensure required training is assigned, completed, and documented on time for all shift employees (cGMP, safety, job skills, etc.)

• Deliver assigned projects, action items, and commitments on schedule

• Identify, lead, and implement initiatives that enhance site capability, performance, and compliance maturity

• Maintain systems and controls to ensure compliance with cGMP, EHS, FDA, and other applicable regulations

• Ensure strict adherence to department procedures and the consistent production of high‑quality therapeutic products

• Foster a positive, inclusive, and equitable work environment that emphasizes accountability, respect, and results

• Lead and coordinate facility GEMBA walks with Manufacturing and support functions (QA, Engineering, Maintenance, Facilities) to ensure inspection‑ready standards

• Represent Manufacturing in meetings, audits, investigations, and cross‑functional initiatives

• Ensure supervisors and employees meet Quality and EHS investigation and closure timelines

• Partner with EHS, Quality, Engineering, and Maintenance to continuously improve safety, quality, and operational performance

What you bring to Takeda

• Bachelor’s degree (preferred in science, engineering, or a related technical field) with 6+ years of manufacturing experience, including 1+ year in a supervisory or people‑leadership role

• Strong working knowledge of manufacturing operations, including Filling, Inspection, and Packaging

• Demonstrated ability to manage multiple priorities through direct and indirect reports in a matrixed environment

• Experience interpreting operational, statistical, and financial data to support informed decision‑making

• Proven ability to resolve technical issues and collaborate effectively with engineering and technical experts

• Experience leading investigations and communicating outcomes through clear, well‑written documentation

• Knowledge of Operational Excellence tools (Lean, Six Sigma), cGMPs, and FDA regulations

• Strong interpersonal and leadership skills with the ability to influence at all levels of the organization

• Ability to lead, coach, and motivate teams in a fast‑paced manufacturing environment

• Strong organizational, administrative, and time‑management skills

• Effective self‑leader with a track record of developing supervisors and manufacturing staff

Important Considerations:

At Takeda, our patients depend on us to deliver safe, high‑quality products. This role operates in a regulated manufacturing environment and requires adherence to strict safety and compliance standards. In this position, you:

• Must be able to lift, push, pull, and carry up to 35 lbs

• Perform a mix of sedentary work and active movement throughout the facility

• Work around moving equipment and machinery

• Operate in controlled environments requiring special safety gear and gowning

• May be exposed to cephalosporins and must not have related allergies

• May require immunizations prior to working in manufacturing areas

• Must follow gowning requirements, including protective clothing for head, face, hands, feet, and body

• May not wear makeup, jewelry, contact lenses, nail polish, or artificial nails in manufacturing areas

• Work in cold, wet, and/or clean‑room environments, including confined spaces as required

• Must be able to work night shifts, weekends, holidays, and overtime as needed in a 24/7 manufacturing operation

Physical demands & working environment

• Ability to lift/push/pull/carry up to 35 lbs and perform prolonged walking throughout the plant to observe operations and conditions.

• Ability to work in controlled environments requiring special gowning and PPE (head/face/hands/feet/body coverage) and follow manufacturing-area restrictions (e.g., no make-up, jewelry, contact lenses, nail polish, or artificial fingernails).

• Ability to work in cold and/or wet environments; may be required to work in a confined area; exposure to clean room and cool/hot storage conditions.

• Ability to support a 24/7 operation, including a 2-2-3 shift model, and work multiple shifts/weekends/holidays as needed; additional time may be required for business needs (e.g., audits, training, slowdown support).

• Up to ~5% travel.

Other Job Requirements (Work schedule / shift):
The preferred schedule is Monday–Friday, 8‑hour overnight shifts. Alternative night‑shift schedules and days may be considered based on business needs. Schedule adjustments may be required to support audits, training, or operational priorities.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Empowering our people to shine:

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

U.S. Base Salary Range:

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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Job Exempt