Director, Real-World Evidence Data Sciences Lead

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Job Description

OBJECTIVES/PURPOSE:

The Real World Data Center of Excellence is meant to foster an environment that simplifies and accelerates collaboration-driven insights that enable data driven business decisions by bringing best practices and standardizing approaches to common questions involving real world data. The Director, Real-World Evidence Data Sciences Lead is responsible for managing the acquisition, processing, and curation of non-Takeda sourced observational RWD, including claims, disease registry, labs and electronic health/medical records (EHR/EMR) data. The role will manage a wide portfolio of data types, with a goal of supporting diverse analyses across Research & Development (R&D); will ensure data transfers follow quality standards; and will coordinate with other stakeholders in R&D to ensure acquisitions satisfy expected analysis plans. In addition, responsibilities include feasibility and exploratory analyses of the RWD, working with observational data sciences colleagues, and collaborating with stakeholders across Takeda, including epidemiologists, translational biologists, biomarker scientists, and biostatisticians. These analyses will provide a better understanding of disease natural history, incidence/prevalence, co-morbidities, treatment patterns, and health and safety outcomes in ‘real world’ patient populations, across a wide variety of serious and unmet diseases, resulting in a high impact to research and early development, clinical development pipeline, and marketed products.

ACCOUNTABILITIES:

• Develop and implement enterprise RWE strategies to efficiently address business needs.

• Collaborate internally and externally to address RWE needs and advise on unmet data needs

• Strengthen partnerships with stakeholders within the organization and externally with platform vendors, RWE innovators, FDA etc.

• Act as a knowledge developer and repository around observational studies, FDA policies, publications etc related to RWE.

• Be at the forefront of advanced technologies like Gen-AI/agentic AI and their applications of Real-World Data.

CORE ELEMENTS RELATED TO THIS ROLE:

• Collaborate with external vendors, Takeda partners, and external organizations responsible for collecting the data

• Ensure data transfers follow quality standards and coordinate with other stakeholders in R&D to ensure acquisitions satisfy expected analysis plans

• Define and implement data transfer, quality control and curation processes, and maintain the data quality pipeline

• Collaborate with other team members to ensure consistency of quality control methods and processes across disparate types of data sourced external to Takeda

• Conduct analyses pertaining to the application of the observational RWE data for diverse stakeholders, including Epidemiology, Value & Access, Translational Biology, Biomarkers; these include specific epidemiology, health outcomes and other observational studies to better understand disease natural history, incidence/prevalence, co-morbidities, treatment patterns, and health and safety outcomes in ‘real world’ patient populations

• Advise on the associated analyses plans using information developed in the execution of the data quality pipelines

• Ensure information is surfaced to ensure the externally sourced data is fit for purpose

• Develop systems, processes and tools (pipelines) which impact enterprise use of our data assets and confirm data quality

• Lead global organizational RWD transparency and education by delivering learning modules on relevant dimensions for users’ qualifications

DIMENSIONS AND ASPECTS:

Technical/Functional (Line) Expertise

• Comprehensive understanding of the pharmaceutical industry and drug development

• Understand and enable analytic infrastructure, including CFR 11 certified software tools, semi-automated, validated SAS algorithms and a skilled data visualization team offer efficient delivery of research and rapid analytics 

Leadership

• Demonstrated ability to work across functions, regions and cultures

• Excellent communicator, able to persuasively convey both ideas and data, verbally and in writing

• Proven skills as an effective team player who can engender credibility and confidence within and outside the company

• Ability to distil complex issues and ideas down to simple comprehensible terms

• Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors for the organization

Interaction

• Effectively navigates the changing external and internal environment and leads others through change by creating and inspiring and engaging workplace

• Cultivates a broad network of relationships throughout Takeda, with affiliates and external partners, in the industry and area of expertise.

• Effectively represents function in negotiations with the ability to resolve conflict in a constructive manner

• Ability to build strong relationships and collaborate effectively with other interfacing Takeda functions

Innovation

• Forward thinking with the ability to recommend, influence and implement organizational change and continuous innovation

• Comfortable challenging the status quo and bringing forward innovative solutions

• Ability to take risks implementing innovative solutions, accelerating time to market

• Identifies opportunities and anticipates changes in the business landscape through an understanding and ongoing assessment of the environment affecting the business.

• Role models respect and inclusion, creating a culture that fosters innovation

Complexity

• Ability to work in a global ecosystem (internal and external) with a high degree of complexity

• Deep expertise required

• Ability to see and understand broader, enterprise level perspective 

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

• Advanced degree in Computer Science, Data Science, Life Sciences, Epidemiology, Bioinformatics, Clinical Informatics or similar technical fields

• 5-8 years relevant work experience with a focus on clinical, observational or RWE data management ingestion, curation, and analysis

• Experience establishing and managing relationships with external vendors and organizations for the acquisition of observational RWD

• Deep understanding of drug development and biopharmaceutical industry, with emphasis on role of observational RWE data

• Experience using hardware and software used to curate, process and analyze data

• Experience with scripting/coding languages (R, Python, Unix scripting, etc.)

• Knowledge of data analysis and trending and familiarity with statistics

• Experience developing and implementing process and data standards

• Strong project management skills, and ability to effectively lead, collaborate and communicate across diverse group of observational RWE data stakeholders (scientific, technical, operational)

• High attention to detail including proven ability to manage multiple, competing priorities

• Demonstrated ability to establish and manage effective business relationships with internal and external stakeholders

This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$174,500.00 - $274,230.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

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