Head of R&D Asset Transition & Integration Office (RATIO)

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Job Description

About the Role

At Takeda, we are guided by our purpose of Better Health for People, Brighter Future for the World and our commitment to patients, our people and the planet. As we continue to evolve our portfolio through acquisitions, partnerships, and divestitures, the ability to transition and integrate assets seamlessly is essential to delivering on our commitments to patients, regulators, and partners.

We are seeking an Executive Director, Head of R&D Asset Transition & Integration Office (RATIO) to lead and scale a strategic capability at the center of R&D operations. This role is responsible for ensuring that all R&D asset transitions—whether integrations, divestments, or wind-downs—are executed with rigor, predictability, and operational excellence.

You will operate at the intersection of science, operations, and strategy—bringing structure to complex transitions while maintaining the highest standards of quality, compliance, and data integrity.

What You’ll Do

As a key leader within R&D Operational Excellence, you will:

• Lead and evolve the RATIO function, overseeing end-to-end execution of R&D asset transitions across integrations, asset wind-downs, divestments, and externalizations

• Drive strategy and execution for complex, global transformation programs—ensuring delivery against timelines, quality standards, and regulatory requirements

• Establish and scale standardized frameworks (tools, ways of working and operating models) to enable repeatable and efficient transition execution

• Oversee critical transition activities, such as TSA support, data transfers, and system decommissioning, etc.

• Partner cross-functionally with stakeholders across R&D, including Business Development, Therapeutic Area Units, Regulatory Affairs, Pharmacovigilance, Quality, IT, and Supply Chain, to align priorities and execution plans

• Ensure compliance and integrity across all transitions, including contractual obligations, regulatory requirements, safety commitments, and data governance

• Provide strategic insights to senior leadership, including risk assessments, resourcing plans, and progress updates

• Drive continuous improvement, incorporating lessons learned to enhance future transition models, capabilities and ways of working

• Maintain organizational readiness to support evolving portfolio strategies, including new acquisitions, asset wind-downs and divestments

What Makes This Role Unique

This role sits at the center of some of the most complex and high-impact work in R&D. You will:

• Lead high-visibility, enterprise-critical initiatives that shape Takeda’s R&D portfolio

• Navigate complex, global transformations involving diverse stakeholders and competing priorities

• Bring clarity and structure to ambiguity, enabling teams to execute with confidence and momentum

• Serve as a trusted partner to senior leadership, influencing decisions that impact patients and the broader organization

Success in this role requires a leader who can balance strategic thinking with operational execution, while building alignment across a highly matrixed, global environment.

What You Bring

• Deep understanding of end-to-end R&D processes, including clinical development, regulatory, safety, and quality systems

• Proven experience leading integration, divestment, or large-scale program management initiatives within a pharmaceutical or biotech environment

• Strong knowledge of data and records management, including regulatory data transfer, system transitions, and archival strategies

• Experience translating complex contractual, regulatory, and scientific requirements into actionable operational plans

• Familiarity with global R&D systems and infrastructure, and how they interact during transitions

Leadership & Impact

• Demonstrated ability to lead in a global, matrixed organization, influencing across functions and regions

• Strong communicator with the ability to simplify complex topics and drive alignment

• Track record of building and developing high-performing teams

• Ability to navigate ambiguity and drive progress, even in highly complex environments

• Commitment to fostering an inclusive, collaborative culture

Education & Experience

• Bachelor’s degree in a scientific or related field required; advanced degree (MBA, PhD, MD) preferred

• 12+ years of relevant experience in the pharmaceutical or biotech industry, including R&D operations, program management, or integration/divestment activities. 

• Demonstrated leadership in global matrix environments. 

Preferred

• Experience in M&A integration/divestment within R&D is preferred.

Additional Information

• May require up to 20% travel (domestic and international)

• This position is currently classified as “hybrid” in accordance with Takeda’s Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$208,200.00 - $327,140.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.