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Lead System Designer for DEP

Bengaluru, Karnataka
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As a trusted global leader and industry partner who is reimagining plasma and exploring its untapped potential, Takeda’s Plasma-Derived Therapies (PDT) Business Unit is dedicated to transforming the lives of patients worldwide who rely on these lifesaving and life-sustaining therapies.

With an 80-year legacy of developing treatments for rare and complex chronic diseases, we thrive on innovation, offering a broad, differentiated portfolio of more than 20 plasma medicines with integrated care solutions to patients in more than 80 countries.

Powered by ~ 17,000 Takeda employees, our ~230 high-quality BioLife donation centers, a dedicated R&D team, and eight world-class plasma manufacturing facilities, we are unleashing data, digital and technology to transform our end-to-end operations and set new industry standards.

This enables us to innovatively and sustainably meet the growing and changing needs of patients, our people, and our planet, today and in the future.

Job ID R0174657 Date posted 02/18/2026 Location Bengaluru, Karnataka

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Job Description

The Future Begins Here

At Takeda, we are leading digital evolution and global transformation. By building innovative solutions and future-ready capabilities, we are meeting the need of patients, our people, and the planet.

Bengaluru, the city, which is India’s epicenter of Innovation, has been selected to be home to Takeda’s recently launched Innovation Capability Center. We invite you to join our digital transformation journey. In this role, you will have the opportunity to boost your skills and become the heart of an innovative engine that is contributing to global impact and improvement.  

At Takeda’s ICC we Unite in Diversity

Takeda is committed to creating an inclusive and collaborative workplace, where individuals are recognized for their backgrounds and abilities they bring to our company. We are continuously improving our collaborators journey in Takeda, and we welcome applications from all qualified candidates. Here, you will feel welcomed, respected, and valued as an important contributor to our diverse team

About the Role

As a Lead System Designer within the Plasma‑Derived Therapies (PDT) Technology ecosystem, you will serve as the senior technical design authority guiding the evolution, intelligence, and structural design of complex enterprise applications. With your experience in system design, distributed systems, engineering leadership, and emerging AI capabilities, you will define design governance, establish reusable design models, and drive product and platform modernization across the PDT landscape.

You will combine deep application and solution design expertise, data‑driven thinking, and AI‑accelerated engineering approaches to ensure PDT systems are scalable, resilient, secure, and intelligence‑enabled. You will mentor technical leads, elevate engineering craftsmanship, and work cross‑functionally to align solutions with business capabilities and enterprise direction.

How You Will Contribute

Application & Solution Design (Expanded and Design‑Centric)

  • Lead application and solution design using clear structural design principles, layered solution models, modular decomposition, and domain‑driven concepts aligned to business capabilities.
  • Create and maintain reusable solution design blueprints, canonical models, service boundaries, and integration models that promote consistency across the PDT ecosystem.
  • Apply Domain‑Driven Design (DDD) techniques such as bounded contexts, aggregates, and ubiquitous language to create maintainable, business‑aligned systems.
  • Design systems using modern patterns including microservices, event‑driven workflows, cloud‑native components, and distributed compute models.
  • Lead solution review forums ensuring designs meet expected standards across performance, resilience, maintainability, and cost effectiveness.
  • Break down complex business needs into clear problem statements and structured design options that engineering teams can execute effectively.
  • Select solution patterns (e.g., CQRS-style design, Saga-style coordination, hexagonal/port‑adapter models) based on suitability, longevity, and simplicity.

Strategic System & Platform Design

  • Guide the overall structural design of PDT applications across NextJS, Node.js, ReactJS/modern front‑end, SQL/NoSQL data layers, Heroku, AWS, EKS, and product-to-platform connectors.
  • Establish design governance, standards, and decision frameworks enabling predictable, high‑quality technical outcomes.
  • Lead system modernization efforts, refactoring initiatives, and cloud‑transition designs across legacy and modern environments.
  • Serve as the design backbone for cross‑product system evolution, ensuring cohesion and consistency across teams.

AI‑Infused Product & Solution Design

  • Introduce Agentic AI concepts into solution models, workflows, operational flows, observability, and developer tooling.
  • Design solutions that incorporate LLMs, embeddings, vector search, reasoning capabilities, autonomous agents, and AI‑powered insights.
  • Establish AI‑ready design patterns supporting semantic data layers, event enrichment, intelligent decisioning, and contextual logic.
  • Partner with data and platform teams to define the data structures, quality expectations, and processing flows required to enable AI‑powered features at scale.

Data & AI Orientation

  • Leverage data dashboards, metrics, operational telemetry, and analytics insights to inform solution design decisions.
  • Embed data quality, lineage, metadata definitions, and consistency rules within system designs to support AI‑driven behaviors.
  • Identify opportunities to apply AI/ML fundamentals to elevate user experience, automate workflows, detect anomalies, and improve operational predictability.
  • Establish design guardrails for responsible use of AI across PDT solutions.

AI‑Augmented Developer Experience & Productivity

  • Champion the adoption of AI‑empowered engineering platforms including GitHub Copilot, or other similar AI tools and intelligent reasoning engines.
  • Define best‑practice guidelines for using AI copilots for design validation, code generation, testing assistance, refactoring, and documentation support.
  • Integrate AI‑assisted processes for generating boilerplate components, design templates, impact analysis, dependency evaluation, and model validation.
  • Continuously evaluate emerging platform AI tooling to drive efficiency, quality, and engineering consistency.

Technical Leadership & Delivery Excellence

  • Conduct solution reviews, design assessments, and technical deep‑dives to maintain high-quality design outcomes.
  • Develop reusable solution artefacts—design templates, reusable service definitions, API models, logical flow diagrams, and deployment models.
  • Ensure solution designs translate into performant, secure, scalable, and maintainable systems.
  • Collaborate closely with product managers, UX designers, senior engineers, data teams, and security specialists to deliver cohesive solutions.
  • Lead estimation, solution planning, risk identification, and stakeholder communication in a clear, structured manner.

Mentorship, Design Governance & Collaboration

  • Mentor technical leads, senior engineers, and emerging designers to strengthen design thinking across teams.
  • Facilitate solution workshops, structured design sessions, and collaborative decision-making forums across PDT.
  • Foster a culture of innovation, clarity of design, technical discipline, and continuous improvement.

Minimum Requirements / Qualifications

  • 14+ years of experience in system design, solution design, and enterprise-scale application development.
  • Expertise across NextJS, Node.js, ReactJS/modern UI frameworks, SQL/NoSQL, Heroku, AWS, EKS, event-driven workflows, microservice-style design, and integration patterns.Skilled in designing and building scalable multi‑cloud and cloud‑agnostic platforms.
  • Proven experience developing secure, resilient, and high‑availability public‑facing web and mobile applications with strong focus on cost optimization and operational efficiency.
  • Strong foundation in distributed caching, zero‑trust design patterns, and SEO optimization.
  • Deep understanding of reusable design patterns, distributed systems, API modeling, domain‑driven concepts, and cloud‑aligned architecture principles.
  • Experienced in architecting multi‑region solutions supporting business continuity, disaster recovery, and fault‑tolerant operations.
  • Strong grounding in modern application engineering practices, including DevSecOps pipelines, IaC principles, security‑by‑design, and continuous validation.

  • Strong communication skills with the ability to simplify complexity and drive cross‑functional alignment.
  • Demonstrated experience establishing design standards and governance practices across teams.
  • Proven ability to mentor engineers and influence solution direction across teams.

Preferred Requirements

  • Experience with containerization and orchestration tools such as Docker and Kubernetes/EKS.
  • Familiarity with secure engineering and DevSecOps tools including CodeQL, SonarCloud, JFrog, and DAST tooling.
  • Experience with event‑streaming technologies (Kafka, AWS SQS/SNS).
  • Hands‑on use of platform AI tools (GitHub Copilot, Azure AI coding tools).
  • Exposure to MLOps concepts or AI‑enhanced system designs.
  • Experience in regulated environments such as healthcare, biotech, or pharmaceuticals.
  • Working understanding of AI/ML fundamentals and hands-on experience integrating AI‑driven features in solutions or engineering workflows.

The Future Begins Here

At Takeda, we are leading digital evolution and global transformation. By building innovative solutions and future-ready capabilities, we are meeting the need of patients, our people, and the planet.

Bengaluru, the city, which is India’s epicenter of Innovation, has been selected to be home to Takeda’s recently launched Innovation Capability Center. We invite you to join our digital transformation journey. In this role, you will have the opportunity to boost your skills and become the heart of an innovative engine that is contributing to global impact and improvement.  

At Takeda’s ICC we Unite in Diversity

Takeda is committed to creating an inclusive and collaborative workplace, where individuals are recognized for their backgrounds and abilities they bring to our company. We are continuously improving our collaborators journey in Takeda, and we welcome applications from all qualified candidates. Here, you will feel welcomed, respected, and valued as an important contributor to our diverse team

BENEFITS:

It is our priority to provide competitive compensation and a benefit package that bridges your personal life with your professional career. Amongst our benefits are:

  • Competitive Salary + Performance Annual Bonus
  • Flexible work environment, including hybrid working
  • Comprehensive Healthcare Insurance Plans for self, spouse, and children
  • Group Term Life Insurance and Group Accident Insurance programs
  • Employee Assistance Program
  • Broad Variety of learning platforms
  • Diversity, Equity, and Inclusion Programs
  • Reimbursements – Home Internet & Mobile Phone
  • Employee Referral Program
  • Leaves – Paternity Leave (4 Weeks) , Maternity Leave (up to 26 weeks), Bereavement Leave (5 calendar days)

ABOUT ICC IN TAKEDA:

  • Takeda is leading a digital revolution. We’re not just transforming our company; we’re improving the lives of millions of patients who rely on our medicines every day.
  • As an organization, we are committed to our cloud-driven business transformation and believe the ICCs are the catalysts of change for our global organization.

#Li-Hybrid

Locations

IND - Bengaluru

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time
Apply Now

Success profile

What makes a successful team member within PDT at Takeda?

  • Bold thinker
  • Systematic
  • Innovative
  • Collaborator
  • Agile
  • Tenacious
At the iHUB, we focus on disruptive innovation within our patient ecosystem that not only focuses on the patients of today, but creates the pathway to meet the patients of tomorrow.

Nat Arlander - Head of the Plasma Innovation Hub in PDT

Our dedicated and specialized PDT R&D organization is uniquely positioned to support the entire patient experience. By challenging decades of established thinking and driving patient-centric innovations, we have the opportunity to have a tremendous impact on those who rely on plasma-derived therapies today and those who can benefit from them in the future.

Kristina Allikmets - Head of PDT, R&D

Our Los Angeles facility

Global Plasma Leaders Collaborate to Accelerate Development of Potential COVID-19 Hyperimmune Therapy Partnership brings together world-leading plasma companies to focus on developing and delivering a hyperimmune immunoglobulin in the global fight against COVID-19.

Changing lives with plasma-derived therapies

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Great Place to Work

    Recognized for our culture and ways of working, we’re proud to be Certified as a Great Place to Work® in 25 countries and regions.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

Exterior of Takeda Building

About our location

Bengaluru, Karnataka


View Map of Bengaluru, Karnataka