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Head of Site Engineering

Pisa, Italy

Pisa, Italy| Ospedaletto, Italy

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On the Global Manufacturing and Supply (GMS) team at Takeda, you’ll be part of a rapidly transforming industry that’s applying technology and data in new ways. Within our agile, innovative, people-centric organization, your work will matter every day as you use your skills to help us manufacture therapies for patients on our four platforms:

  • Small Molecules
  • Biologics
  • Plasma
  • Cell and Gene

As part of the GMS team, you'll have the opportunity to pursue unique experiences and build new skills, and you'll know that the work you do every day makes an impact — on our patients, our people, our planet, and on yourself.

Job ID R0146959 Date posted 03/17/2025 Location Pisa, Italy

Pisa, Italy| Ospedaletto, Italy

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Job Description

OBJECTIVES/PURPOSE

  • Lead and manage engineering operations for manufacturing operations in Pisa plant.
  • Provide holistic engineering and maintenance support to the site to sustainably achieve capacity plans and fulfillment targets.
  • Maintain equipment and facilities, performing facilities management including operations of utilities and critical systems, providing engineering technical support and capital planning and execution.

ACCOUNTABILITIES

  • Responsible for performance management and professional development of direct reports.
  • Accountable for performance management and professional development of engineering personnel.
  • Allocates resources, assigns priority to tasks and acts as an advisor to Site senior management in the delivery of value-added services for Pisa Site.
  • Manages budgets and contract resources.
  • Provides management oversight to ensure that Facilities, Utilities and Equipment are properly maintained, fit for intended use, operated in a safe and efficient manner, and are compliant with all regulatory requirements.
  • Provides management oversight of delivery of coordinated major maintenance activities including scheduled plant shutdowns. Ensure organizational agility in order for timely response and resolution to operational issues.
  • Accountable for development of technical subject matter expertise and provision of adequate engineering resources (internally and externally) to ensure system reliability, robustness and maximum availability.
  • Ensures delivery of compliant and robust engineered solutions to improve reliability and efficiency of systems and equipment based upon best practices and operational periodic reviews.
  • Supports the planning and execution of site capital investment projects to ensure that projects are on time and on budget.
  • Supports and control the site CAPEX and equipment lifecycle
  • The position has the role of “Dirigente/Executive for Safety Aspects according to the legislation
    Italian art. 2 paragraph 1 letter d) of Legislative Decree 81/08

CORE ELEMENTS RELATED TO THIS ROLE

  • Implement strategic plans to improve engineering capabilities, building toward the factory of the future.
  • Introduce new technologies that enhance automation, digitalization, reliability, safety, and sustainability in an environment that embraces innovation.
  • Lead and coach others to develop their careers and achieve personal growth.
  • Identify solutions to complex problems while maintaining the highest quality standards and complying with regulatory requirements.
  • Align site priorities with business unit engineering and global functions programs in collaboration with stakeholders on cross-functional teams.
  • Bring productivity to the next level through development and execution of detail-oriented financial plans and budgets to meet key performance indicators (KPIs) and production goals
  • Drive initiatives to incorporate green manufacturing techniques that increase sustainability and reduce our environmental impact.
  • Oversee lifecycle management of facilities, equipment, and assets while ensuring Good Engineering Practices and compliance with environmental health and safety (EHS) requirements.

Technical/Functional (Line) Expertise

  • Manages technical records and diagrams.
  • Manages relationships with technical third parties such as equipment suppliers, directly handling service requests and agreements.
  • Promotes and leads the exchange of technical knowledge within and outside the site.

Leadership

  • Ensures the technical competence of process engineers and technicians through the adoption of high standards, efficient methodologies, a data-centric approach, and a dedication to fundamental engineering principles.
  • Provides strategic oversights and acts as an advisor or trainer to subordinate manager or staff members.
  • Create an environment that inspires and enables people to move organization forward

Interaction

  • Internal/External functions/resources
  • Acts as an industry expert for the site within the global network.

Innovation

  • Promotes continuous improvement of processes and equipment, ensuring alignment with the latest internal and external rules and regulations.
  • Constructively challenges outdated norms and traditions and provides alternatives; adopts breakthrough ideas, innovations, and initiatives 

Complexity

  • Strategic project planning and execution within challenging timelines and environment

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

  • Master degree in engineering (mechanical, chemical, electronic, industrial, automation, etc…)
  • In depth technical proficiency on pharmaceutical systems and equipment
  • Good knowledge of cGMPs and pharma/HSE rules and standards
  • 10+ years experience in pharmaceutical Company with specific focus on process, maintenance, technical support, process/equipment development
  • Fluent in English
  • Exceptional ability to manage simultaneous activities, competing priorities, and challenges
  • Leadership / influence
  • In-depth knowledge of the sterile production process and equipment
  • Strong ability to work and communicate effectively with the team and peers within a manufacturing and engineering organization. This includes excellent communication skills: written and verbal
  • Prioritization & project management skills
  • High-level problem-solving / root cause investigation skills
  • Creative capacity for developing new ways to do things better, cheaper, faster

Locations

ITA - Pisa

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time
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Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance