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Job Description

Takeda Vaccines is looking for a Scientist to join our Critical Reagents and Biochemistry team in our Cambridge, MA office .

How you will contribute:  

As a Scientist you will join our biophysical characterization / critical reagents / analytical development lab. You will be a highly responsible and self-motivated individual supporting the development and manufacturing of Dengue vaccine. If you have previous experience with working with viruses, that is a plus.

You will focus on:

• Characterization of critical reagents (mAbs, mAb conjugates, etc.)

• Development and application of analytical methods for characterization of Dengue virus drug substance and drug product,

• Lab operations and maintenance (ensuring equipment readiness and maintenance, ordering and tracking the materials and supplies, etc).

• You will contribute to execution of biophysical and biochemical characterization of different biologics (nucleic acids, proteins, viruses etc.)

• You will collaborate cross-functionally with Analytical Development and Quality Control teams, as well as colleagues from other sites or external organizations (such as CROs), to drive projects forward.

• You will author or co-author internal operational protocols and external publications.

Minimum Requirements/Qualifications: 

• Ph.D. or M.S. in Protein Chemistry, Bioengineering, Chemical Engineering, Biochemistry, Biophysics, Pharmaceutical Sciences) with 3-5 years of relevant biopharmaceutical industry experience preferred.

• Hands-on experience in protein biochemical and biophysical characterization, developability assessment, and stress stability studies in support of formulation development.

• Detailed knowledge of protein structure, protein stability, biophysical characterization, formulation screening, and product development.

• Strong expertise in protein biophysical and biochemical characterization techniques, including but not limited to:  chromatography (SEC, IEX, RP, HIC, etc.), Thermal / conformational stability techniques (DSC, DSF), Colloidal Stability / Particle sizing, counting, and characterization techniques (NTA, DLS, SEC-MALS, aFFF-MALS, Zeta Potential, etc.), spectroscopy (UV-vis, fluorescence, NMR, Raman, FTIR), capillary electrophoresis (CE) or SDS-PAGE Lab-on-a-chip (GX2), Mass Spectrometry (sample prep/digestion, peptide mapping, host cell protein characterization, virus maturity characterization).  

• Individual must be willing and able to learn new technologies as needed. 

• Experience in Molecular and Cellular Biology would be a plus.

• Knowledge of bioconjugation can also be an advantage.

• Demonstrated track record of independent thinking, creativity, and scientific accomplishment.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$111,800.00 - $175,670.00

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.