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Research Sr. Scientist, Biologics In Vitro Pharmacology (BIVP)

Boston, Massachusetts
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  • Job Level: Senior
  • Travel: Minimal (if any)

At Takeda, we strive to provide transformational opportunities for every member of our team, and we empower our people to take charge of their futures. In an environment that fosters lifelong learning and a growth mindset, you’ll have the support you need to thrive — at work and beyond.

Job ID R0152612 Date posted 05/16/2025 Location Boston, Massachusetts

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Job Description

Objective / Purpose:

Global Biologics (GB) mission is the discovery of transformative innovative biologics therapeutics to support Takeda’s pipeline and advance novel therapeutics into clinical development in Takeda’s three therapeutic areas of interest: Oncology (immuno-oncology, cell therapies), Gastroenterology and Neuroscience.

Biologics In Vitro Pharmacology (BIVP) role is to identify the therapeutics candidates that have the desired biological activity and select the best candidates for further preclinical and clinical development.

This role will provide essential scientific guidance and make strategic decisions to ensure the delivery of the critical functions of BIVP.

ACCOUNTABILITIES:

  • Independently designs, develops, and executes research experiments/studies with high scientific rigor and leads the interpretation of study results.

  • Designs, executes and validates a variety of assays to understand mechanism of action and characterize biologics.

  • Records experimental design and results in a timely and accurate manner and prepares study reports for internal or regulatory use.

  • Develops and oversees novel scientific projects and manages the work of others directly or in a matrixed structure.

  • Provides broad assay development support for early-stage drug discovery projects in the GI tract and inflammation disease area.

  • Acts as a senior scientific consultant, providing technical and strategic leadership for research project implementation and coordination.

  • Independently finds solutions and develops strategies within his/her area of expertise, uses breadth of knowledge of other disciplines and acts as a scientific resource for BIVP.

  • Scientifically assesses and recommends vendors and outsources nonclinical studies to appropriate contract research organizations.

  • Collaborates with automation engineers to identify suitable ways to utilize laboratory automation for the execution of a variety of cell-based assays.

  • Contributes to multiple projects, interfacing with project teams to meet timelines for project progression.

  • Presents research findings clearly and effectively at internal and external meetings.

DIMENSIONS AND ASPECTS

Technical/Functional (Line) Expertise

  • Experienced in the design, development and implementation of in vitro cell-based functional assays to study target-specific drug effects.

  • Knowledgeable and experienced in cell biology and antibody characterization.

  • Experienced with cell-based functional assay platforms, including, but not limited to, on-cell binding, reporter assay, Alphalisa, MSD, flow cytometry, cell adhesion, cell migration, and imaging.

  • Experience in troubleshooting, assay optimization, and data quality control are a plus.

  • Skilled in data analysis, interpretation, and data reporting.

  • Experience and knowledge in diseases of the GI tract, such as liver fibrosis and inflammatory bowel disease, is a plus.

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

  • PhD degree in biomedical, biological science, biochemistry, immunology, oncology, biotechnology, or related scientific discipline with 3+ years of experience, or MS with 9+ years of experience, or BS with 11+ years of experience.

  • Industry standard experience with data record creation and maintenance.

  • Broad technical knowledge of biochemical science, HTP functional assays and automation experience.

  • Ability to work in a fast-paced environment; self-driven, creative, with a strong team-oriented mentality, positive attitude and effective project management skills.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$137,000.00 - $215,270.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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Where you fit in

Our team at Takeda is tackling some of the most challenging problems in drug discovery and development. As the newest member of our Research team, you’ll conduct purposeful, meaningful work on groundbreaking modalities that may lead to breakthrough drugs.

With our deep investment in next-generation technologies, you’ll have the resources and support to do your best work. As a part of our team, you’ll connect with brilliant minds inside and outside of Takeda. We are committed to collaborating with academia and emerging biotech companies to expand our reach and impact in cell therapy, gene therapy and data sciences.

Our team’s wide-ranging expertise includes medicinal chemistry, genomics datasets, immunofluorescence, high content imaging, flow cytometry, transcriptional profiling, multi-step synthesis, multimodal genetics, pharmacokinetics and much more. Whatever area inspires you, your work will support the progression of an innovative, industry-leading discovery pipeline and make an impact that matters to patients and society.

A career in Research at Takeda will give you everything you need to succeed professionally — and make a difference to patients, people and the planet.

  • Design and carry out experiments

  • Manage multiple projects

  • Document data

  • Mentor other scientists

Along with incredibly passionate colleagues, there’s a clear commitment to invest in the best facilities and the right equipment needed to successfully perform world-class science.

Christina Alves - Head of Biotherapeutics Process Development

Our pipeline

Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.

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What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.

  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.

  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.

  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.

  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.

  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

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