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Director, Pathology Drug Safety Research and Evaluation (DSRE), Head of Investigative Pathology (iPath)

Boston, Massachusetts
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  • Job Level: Senior
  • Travel: Minimal (if any)

At Takeda, we strive to provide transformational opportunities for every member of our team, and we empower our people to take charge of their futures. In an environment that fosters lifelong learning and a growth mindset, you’ll have the support you need to thrive — at work and beyond.

Job ID R0124059 Date posted 07/09/2024 Location Boston, Massachusetts

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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Director, Pathology Drug Safety Research and Evaluation (DSRE), Head of Investigative Pathology (iPath) in Cambridge, MA, where you will manage a team of scientists and technicians, oversee all pathology activities, and act as the pathology subject matter expert on cross-functional research and development teams. The Head of Investigative Pathology is a strategic and hands-on leadership role responsible for driving pathology support for programs, providing expert guidance and oversight in investigative and toxicologic pathology within Drug Safety Research and Evaluation (DSRE). This role combines lab management and project support with a focus on delivering high-quality, timely data to primarily support early-stage drug discovery and toxicology studies.

As part of the DSRE, Pathology team, you will report to the Senior Director DSRE - Pathology and you will partner with senior management and R&D teams to align pathology goals with overall program objectives.

How you will contribute:

  • Manage the iPath Laboratory, ensuring compliance with all regulatory and safety standards.
  • Lead, mentor, and develop a team of scientists, and technical staff to achieve project milestones.
  • Manage lab operations, budgeting, resource allocation, and workflows to optimize efficiency and productivity.
  • Proven leadership experience in managing pathology labs and teams in a discovery and nonclinical setting.
  • Oversee and drive the development of investigative pathology capabilities within the team, including innovative methods to advance project outcomes.
  • Provide scientific direction and investigative pathology expertise to project specific IHC and ISH deliverables in collaboration with the project pathologist.
  • Serve as an integral member on discovery and development project teams to collaborate with project and R&D leadership across Takeda to ensure transition of programs into development.
  • Responsible for recognizing critical issues as a highly skilled specialist, effectively communicate their implications to a broad audience and develop strategies investigate/derisk these data to impact the project team strategy and decision making.
  • Collaborate with DSRE project representatives, cross-functional project teams, Global Head of Pathology and Drug Safety Therapeutic Area Leaders in the development and execution of nonclinical safety and investigative strategies for discovery and development stage programs.
  • Provide training and knowledge sharing for pathology-related aspects across the R&D teams.
  • Participate in local and national toxicology/pathology meetings and represent Takeda in professional society committees, working groups and cross industry consortia.

Minimum Requirements/Qualifications:

  • DVM (or equivalent) and Ph.D. degree in a scientific discipline are both required.
  • Board certified by the American College of Veterinary Pathologists (ACVP), European College of Veterinary Pathology (ECVP) or Japanese College of Veterinary Pathology (JCVP) is required.
  • Pharmaceutical drug development experience preferably including as a project team Pathologist (10+ years).
  • Proven leadership experience in managing pathology labs and teams in a discovery and nonclinical setting.
  • In-depth understanding of molecular biology with strong expertise in toxicologic pathology and its application to drug discovery and development.
  • Excellent communication (written and oral), leadership, and team-building skills, with the ability to work in a collaborative environment.
  • Proficiency with Microsoft Office suite, HALO/HALO Link, Pristima (or other pathology data capture systems), Patholytix.

More About Us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy. This position requires the candidate to come onsite to Cambridge location minimum 5x/month.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes
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Where you fit in

Our team at Takeda is tackling some of the most challenging problems in drug discovery and development. As the newest member of our Research team, you’ll conduct purposeful, meaningful work on groundbreaking modalities that may lead to breakthrough drugs.

With our deep investment in next-generation technologies, you’ll have the resources and support to do your best work. As a part of our team, you’ll connect with brilliant minds inside and outside of Takeda. We are committed to collaborating with academia and emerging biotech companies to expand our reach and impact in cell therapy, gene therapy and data sciences.

Our team’s wide-ranging expertise includes medicinal chemistry, genomics datasets, immunofluorescence, high content imaging, flow cytometry, transcriptional profiling, multi-step synthesis, multimodal genetics, pharmacokinetics and much more. Whatever area inspires you, your work will support the progression of an innovative, industry-leading discovery pipeline and make an impact that matters to patients and society.

A career in Research at Takeda will give you everything you need to succeed professionally — and make a difference to patients, people and the planet.

  • Design and carry out experiments

  • Manage multiple projects

  • Document data

  • Mentor other scientists

Along with incredibly passionate colleagues, there’s a clear commitment to invest in the best facilities and the right equipment needed to successfully perform world-class science.

Christina Alves - Head of Biotherapeutics Process Development

I feel especially lucky to be able to work with colleagues across the industry to meet a unified goal.Takeda is paving the way for how research will be conducted in the future.

Daniel Scheibe - Senior Manager Operations, Systems Engineering, Drug Discovery Sciences

Our pipeline

Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.

Learn more

What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

Exterior of Takeda Building

About our location

Boston, Massachusetts


View Map of Boston, Massachusetts

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