About the Role:

As a key member of the Manufacturing Sciences – Commercial Manufacturing Support Laboratory group, you will provide technical and scientific support of upstream, clarification and ultrafiltration processes for commercial production of Biologics, including process and product investigations/troubleshooting, continuous process improvement and life-cycle management, technology transfer and process validation. You may contribute as a member of multiple cross- functional teams and may interact with other departments within Takeda, including Manufacturing, QA, QC, PD, Engineering and RA. You will report to Head of Manufacturing Science, Upstream.

This is a hybrid role.

How you will contribute:

• Assist in design and execution of continuous process improvements, aimed at improving robustness, capacity, and productivity.
• Provide technical expertise in identifying opportunities/areas, planning, designing and conducting experiments, analyzing data and documenting results towards continuous process improvement, including reducing recurring deviations, and increasing level of safety and/or compliance.
• Provide high quality of written study proposals, research and development reports, and investigation reports.
• Provide technical expertise in troubleshooting and root cause analysis for process discrepancies and quality investigations of a complex technical nature
• Independently design and execute cell culture experiments related to characterization of cell culture parameters
• Apply engineering principles in scaling up from bench to pilot plant or GMP manufacturing scale.
• Manage and maintain data in an organized manner. This includes keeping proper GLP lab documentation, authoring technical reports, tech transfer documents and preparing scientific presentations as needed.
• Demonstrate teamwork/collaboration and the ability to communicate appropriately and effectively.
• Be customer focused, results oriented, science driven and embrace Takeda's values.
• Have the attitude to proactively learn new technologies and manage changes in cell culture process development and improvement.
• Execute cell culture or clarification process improvement, troubleshooting and manufacturing technical support.
• Assist in analyzing complex technical problems, then finding and implementing solutions.
• Apply fundamental scientific and biological principles to practical technical challenges.
• Under supervision, plan and execute experimental studies.
• Work with his/her supervisor and coworkers in managing multiple work streams and projects.
• Provide input to departmental management towards making functional decisions.

What you bring to Takeda:

• BS in Biochemistry or Chemical Engineering or related disciplines
• 1 year work experience in the biotechnology industry.
• Ability to work in a fast-paced environment with demonstrated capacity to juggle multiple tasks and demands.
• Hands-on experience in cell culture or depth filtration, ultra-filtration in lab or manufacturing scale would be ideal.
• Knowledge of GMP working environments would be ideal.
• Have basic knowledge of mammalian cell culture

Important Considerations:

At Takeda, our patients rely on us to deliver quality products. As a result, we must follow strict rules in our manufacturing facilities to ensure we are not endangering the quality of the product. In this role, you may:

• Work in a controlled environment requiring special gowning and wear protective clothing over the head, face, hands, feet and body. This may include additional hearing protection for loud areas.
• Need to remove all make-up, jewelry, contact lenses, nail polish and/or artificial fingernails while in the manufacturing environment.
• Work in a cold, wet environment.
• Work multiple shifts, including weekends, or be asked to work supplemental hours, as necessary.
• Work around chemicals such as alcohol, acids, buffers and Celite that may require respiratory protection.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

#GMSGQ #ZR1 #LI-MA1

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.