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Principal Scientist, Small Molecule In Vitro Pharmacology (IVP) / 主任研究員

Fujisawa, Kanagawa
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  • Job Type: Full Time
  • Job Level: Senior
  • Travel: Minimal (if any)

At Takeda, we strive to provide transformational opportunities for every member of our team, and we empower our people to take charge of their futures. In an environment that fosters lifelong learning and a growth mindset, you’ll have the support you need to thrive — at work and beyond.

Job ID R0146550 Date posted 03/25/2025 Location Fujisawa, Kanagawa

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Job Description

タケダの紹介

タケダは「世界中の人々の健康と輝かしい未来に貢献する」ことを企業の存在意義(パーパス)としています。そして目指す未来を共有しながら、一人ひとりが自分の可能性を引き出し、お互いの個性を認め合う、多様性にあふれた先進的な組織作りに取り組んでいます。私たちと一緒に、世界中の人々のいのちに貢献し、さらなる成長と活躍を目指しませんか。

タケダはグローバルな研究開発型のバイオ医薬品のリーディングカンパニーです。従業員は創業時から受け継いできたタケダの価値観であるタケダイズム(誠実=公正・正直・不屈)を道しるべとしながら、患者さんに寄り添い(Patient)人々と信頼関係を築き(Trust)社会的評価を向上させ(Reputation)持続可能な事業を発展させる(Business)を日々の行動指針としています。

”Better Health for People, Brighter Future for the World” is the purpose of a company. We aim to create a diverse and inclusive organization where people can thrive, grow and realize their own potential while enabling our purpose. We continue to innovate and drive changes that will transform the lives of patients. We’re looking for like-minded professionals to join us.

Takeda is a global values-based, R&D-driven biopharmaceutical leader. We are guided by our values of Takeda-ism, which has been passed down since the company’s founding. Takeda-ism incorporates Integrity, Fairness, Honesty, and Perseverance, with Integrity at the core. They are brought to life through actions based on Patient-Trust-Reputation-Business, in this order.

募集部門の紹介

In vitro pharmacology (IVP)は、インビトロでのアッセイ系の構築を行い、低分子化合物等の薬物候補化合物のスクリーニング、活性評価、キャラクタリゼーションを行います。薬理グループ、メディシナルケミストリーグループ、グローバルの関連部門と密に連携し、リード化合物や開発化合物の創出における重要な役割の一部を担います。

職務内容

  • インビトロアッセイ系構築

  • スクリーニングカスケードの提案と実施

  • 分子生物学的アプローチによる、薬物作用のメカニズム解析

  • 化合物およびアッセイに関連するデータベースの構築とその活用

  • CROへの技術移管および案件管理

  • 社内プラットフォーム(研究機器、IT、業務フロープロセスなど)の整備

応募要件

<学歴> 

  • In vitroアッセイに関連する実務歴が5年以上

  • 理系大学院博士課程卒以上、あるいは相応する分子生物学に関する専門性

<実務経験>

  • インビトロアッセイ系構築および化合物評価と解析(cell-based assay, biochemical assay, biophysical assayなど)

  • 96-wellおよび384-wellプレートを用いたミディアム/ハイスループット機器による検出を伴う実験

  • エクセル、およびグラフ作成ソフトを活用したデータの詳細解析

  • 構築した評価系の他の実務担当者への技術移管

<スキル・資格>

  • 分子生物学関する基礎知識

  • カルタヘナ法を含む遺伝子組み換え実験に関する規制や法律、臨床検体取り扱い時のバイオセイフティーに対する十分な知識と理解

  • 統計学的手法などを用いた、アッセイの精度や誤差に対する分析力

<語学>

  • TOEIC中級レベル以上(600点以上程度)英語語学力が望ましい(英文メールでのコミュニケーション、英文文献からの情報収集、英文プロトコールの翻訳および作成が滞りなく行うことができるレベル)

  • グローバルカンパニーで務める上での、英語語学力の向上に対する十分な意欲

<その他>

求める人物像

  • 非臨床の創薬プロジェクトにおいて、チームの一員となり、プロジェクトの推進や意思決定のために必要な要素を、分子生物学的観点から考察することができる。あるいは、その強い学習意欲がある。

  • 年齢、性別、国籍などを問わず、チームのダイバーシティーを歓迎できる。

仕事のやりがい

  • ケミストリーメンバーと密に連携を行う、グローバルチームのメンバーに加わって頂きます。湘南研究所の新たなin vitroアッセイプラットフォームを築き上げる重要な役割を果たします。

本職務で身につくスキル・経験

  • 領域横断的な幅広い創薬コンセプトに携わります。

  • 最先端の分子生物学的手法にキャッチアップし、化合物のスクリーニングやキャラクタリゼーションを行います。

  • 精度(質)、スループット(スピード)、コストといった観点から研究活動全体を評価する側面を有するため、個々人のビジネスセンスが磨かれます。

  • グローバルメンバーとのコミュニケーションの機会があります。

その他

待遇

諸手当:通勤交通費、借家補助費、勤務時間外手当など

昇給:原則年1回 

賞与: 原則年2回

勤務時間:本社(大阪市中央区・東京都中央区)9:00~17:30 、工場(山口県光市・大阪市淀川区)8:00~16:45 、(成田)8:45~5:15 、 研究所(神奈川県藤沢市)9:00~17:45

休日:土曜、日曜、祝日、メーデー、年末年始など(年間123日程度)

働き方関連制度:フレックスタイム制、テレワーク勤務制導入(対象社員)

休暇:年次有給休暇、特別有給休暇、傷病休暇、ファミリーサポート休暇、産前産後休暇、育児休暇、子の看護休暇、介護休暇

Takeda Compensation and Benefits Summary:

  • Allowances: Commutation, Housing, Overtime Work etc.

  • Salary Increase: Annually, Bonus Payment: Twice a year

  • Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/ Yamaguchi) 8:00-16:45, (Narita) 8:30-17:15, Research Site (Kanagawa) 9:00-17:45

  • Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)

  • Paid Leaves: Annual Paid Leave, Special Paid Leave, Sick Leave, Family Support Leave, Maternity Leave, Childcare Leave, Family Nursing Leave.

  • Flexible Work Styles: Flextime, Telework

  • Benefits: Social Insurance, Retirement and Corporate Pension, Employee Stock Ownership Program, etc.

Important Notice concerning working conditions:

  • It is possible the job scope may change at the company’s discretion.

  • It is possible the department and workplace may change at the company’s discretion.

Locations

Fujisawa, Japan

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time
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Where you fit in

Our team at Takeda is tackling some of the most challenging problems in drug discovery and development. As the newest member of our Research team, you’ll conduct purposeful, meaningful work on groundbreaking modalities that may lead to breakthrough drugs.

With our deep investment in next-generation technologies, you’ll have the resources and support to do your best work. As a part of our team, you’ll connect with brilliant minds inside and outside of Takeda. We are committed to collaborating with academia and emerging biotech companies to expand our reach and impact in cell therapy, gene therapy and data sciences.

Our team’s wide-ranging expertise includes medicinal chemistry, genomics datasets, immunofluorescence, high content imaging, flow cytometry, transcriptional profiling, multi-step synthesis, multimodal genetics, pharmacokinetics and much more. Whatever area inspires you, your work will support the progression of an innovative, industry-leading discovery pipeline and make an impact that matters to patients and society.

A career in Research at Takeda will give you everything you need to succeed professionally — and make a difference to patients, people and the planet.

  • Design and carry out experiments

  • Manage multiple projects

  • Document data

  • Mentor other scientists

Along with incredibly passionate colleagues, there’s a clear commitment to invest in the best facilities and the right equipment needed to successfully perform world-class science.

Christina Alves - Head of Biotherapeutics Process Development

Our pipeline

Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.

Learn more

What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

Exterior of Takeda Building

About our location

Fujisawa, Kanagawa


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