
Preclinical Researcher for Neuroscience Drug Discovery
Fujisawa, Kanagawa- Job Type: Full Time
- Job Level: Senior
- Travel: Minimal (if any)
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Job Description
タケダの紹介
タケダでは常に患者さんを中心に考え、世界中の人々により健やかで輝かしい未来をお届けすることを目指してきました。そして従業員一人ひとりにそれぞれの能力と熱意に応じた成長の機会を提供することにも組んで取り組んでいます。私たちと一緒に、世界中の人々のいのちに貢献し、さらなる成長と活躍を目指しませんか。
タケダは業界を牽引するグローバルリーダーです。従業員は四つの優先順位(患者さん中心、社会との信頼関係構築、レピュテーションの向上、事業の発展)とタケダイズム(誠実=公正・正直・不屈)のもと一致団結しています。タケダイズムは私たちの信念であり正しい方向へ導く羅針盤です。私たちは日々の業務においてタケダイズムを体現しています。
Takeda is unwavering in our commitment to patients. With the patient at the center of everything we do, we continue to innovate and drive changes that will better their lives - we’re looking for like-minded professionals to join us.
Takeda is a global industry leader –we are united by our four priorities (Patients, Trust, Reputation, and Business) and our shared values of Takeda-ism: Integrity, Fairness, Honesty, and Perseverance. Takeda-ism is more than just a word. It’s a belief and a mindset which guides our decisions, behaviors, and interactions. It’s how we strive to work and live, every day.
Objective / Purpose:
- Engages in preclinical drug discovery activities for diseases in Neuroscience area, specifically neurodegenerative and rare neurological diseases, under the direct supervision from the Associate Director.
- Leads or participates in cross-functional drug discovery research projects as a biological research representative and selects clinical drug candidates
- Develops or introduces cutting-edge technologies to enhance scientific expertise of Neuroscience DDU.
- 主席研究員の直接指導のもと、ニューロサイエンス領域、特に神経変性疾患および希少神経疾患に関する前臨床創薬活動に従事する。
- 生物学的研究担当者として、クロスファンクショナルな創薬研究プロジェクトを主導または参加し、臨床候補薬の選定を行う。
- ニューロサイエンス創薬ユニットの科学的専門性を高めるため、最先端技術の開発または導入に取り組む。
Accountabilities:
- Explores and identifies potential drug targets for neuroscience diseases, particularly neurodegenerative diseases and rare neurological diseases.
- Establishes and performs in vitro assays for screening of drug candidate compounds.
- Performs in vitro evaluation for validation of hit compounds using genes, cells, proteins, viruses, etc. to elucidate the mechanism of action.
- Establishes and conducts in vivo pharmacological evaluations in animals such as mice, rats, and monkeys to optimize candidate compounds.
- Ensures reliability of data by using reproducible experimental techniques and appropriate data analysis methods.
- Leads or participates in cross-functional drug discovery research projects as a biological research representative, working with internal partners (GC, DSRE, DMPK, PS, TAU, etc.) to select clinical drug candidates.
- Develops or introduces cutting-edge technologies and methods for drug discovery in the Neuroscience field.
- ニューロサイエンス領域、特に神経変性疾患および希少神経疾患における潜在的な薬剤ターゲットを探索・特定する。
- 創薬候補化合物のスクリーニングのためのin vitroアッセイを確立し実施する。
- 作用機作を解明するために遺伝子、細胞、タンパク質、ウイルスなどを用いて、ヒット化合物のバリデーションのためのin vitro評価を実施する。
- 候補化合物の最適化のためにマウス、ラット、サルなどの動物を用いたin vivo薬理評価を確立し、実施する。
- 再現性のある実験技術と適切なデータ解析手法を用いて、データの信頼性を担保する。
- 生物学的研究担当者として、クロスファンクショナルな創薬研究プロジェクトを主導または参加し、社内パートナー(GC、DSRE、DMPK、PS、TAUなど)と協働しながら臨床候補薬の選定を行う。
- ニューロサイエンス分野の創薬において、最先端技術や手法の開発・導入に取り組む。
Education & Competencies (Technical and Behavioral):
- Has an M.S. equivalent in relevant fields such as pharmaceutical science or science and has at least 3 years of industry experience in the field of drug discovery as a pharmacologist or biologist. Or has a medical degree and has at least 3 years of research experience in academia or industry.
- Has highly knowledgeable in pharmacology or biology in Neuroscience drug discovery and ability to produce high-quality and reproducible data.
- Has general knowledge of the drug discovery process from target identification to clinical candidate selection.
- Has an ability to develop unique strategies and author/publish research papers with higher impact.
- Has excellent business skills and manners such as logical thinking, strategy planning, self-management, etc.
- Has good writing, verbal communication, and presentation skills in Japanese and English.
- Has an open mind-set willing to learn and reach out to innovative science.
- Takes initiatives and provides opinions to achieve goals of the team.
- 薬学や科学など関連分野の修士相当の学位を有し、薬理学者または生物学者として創薬分野で少なくとも3年以上の企業での就業経験があること。または、医学の学位を有し、アカデミアまたは企業で少なくとも3年以上の研究経験があること。
- ニューロサイエンス創薬における薬理学または生物学に関して高度な知識を持ち、高品質で再現性のあるデータを作成する能力があること。
- ターゲット同定から臨床候補化合物の選定に至る創薬プロセス全般に関する一般的な知識を有すること。
- 独自の戦略を立案し、インパクトの高い研究論文の執筆・発表ができる能力を持つこと。
- 論理的思考、戦略立案、自己管理などの優れたビジネススキルおよびマナーを備えていること。
- 日本語および英語において優れた文章作成、口頭コミュニケーション、プレゼンテーション能力を持つこと。
- 革新的な科学を学び、積極的に取り組むオープンなマインドセットを持つこと。
- チームの目標達成に向けて率先して行動し、意見を述べることができること。
タケダのDE&I
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Takeda Compensation and Benefits Summary:
Allowances: Commutation, Housing, Overtime Work etc.
Salary Increase: Annually, Bonus Payment: Twice a year
Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/ Yamaguchi) 8:00-16:45, (Narita) 8:30-17:15, Research Site (Kanagawa) 9:00-17:45
Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)
Paid Leaves: Annual Paid Leave, Special Paid Leave, Sick Leave, Family Support Leave, Maternity Leave, Childcare Leave, Family Nursing Leave.
Flexible Work Styles: Flextime, Telework
Benefits: Social Insurance, Retirement and Corporate Pension, Employee Stock Ownership Program, etc.
Important Notice concerning working conditions:
It is possible the job scope may change at the company’s discretion.
It is possible the department and workplace may change at the company’s discretion.
Locations
JPN - Kanagawa - FujisawaWorker Type
EmployeeWorker Sub-Type
RegularTime Type
Full timeOur pipeline
Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.
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