2025 U.S Summer Internship Program: Analytical Development (Synthetic Molecules) Intern

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Job Description

The Structure Characterization Group, part of the Analytical Development Department, is dedicated to elucidating the molecular structures of pharmaceutical compounds. Our team utilizes advanced analytical techniques, including NMR and MS, to determine the detailed structural information of compounds in drug products, drug substances, intermediates, impurities, etc. By providing comprehensive structural insights, we support the development, optimization, and quality control of Takeda’s innovative therapies across difference stages, ensuring they meet rigorous standards of safety and efficacy.

Job Description:

As an intern, you will support in silico (computational) predictions of drug degradation pathways and perform experiments to characterize potential impurities. This is a unique opportunity to gain hands-on experience in predictive computational models and analytical lab techniques, essential for ensuring the stability and safety of pharmaceutical products. You will work closely with experienced scientists and contribute to data analysis, reporting, and the interpretation of results.

How You Will Contribute:

• Computational Prediction: Utilize in silico tools to predict drug degradation pathways and potential impurities. Work with advanced prediction software and computational models to support drug stability assessments.
• Laboratory Characterization: Conduct wet lab experiments to identify, isolate, and characterize drug impurities. Operate laboratory instruments such as HPLC, LC-MS, and other relevant analytical tools.
• Data Analysis: Analyze results from both computational predictions and laboratory tests to assess impurity profiles and validate predictions.
• Documentation: Maintain detailed laboratory notebooks and records of computational and experimental results. Assist in preparing reports and summaries for an internal database.
• Collaboration: Work in close coordination with the analytical development team.

Internship Development Opportunities:

• Hands-on experience in predictive computational modeling and wet lab analysis of drug stability.
• Exposure to real-world challenges in drug development and pharmaceutical quality control
• Mentorship from industry professionals and the opportunity to network within the pharmaceutical industry.

Job Requirements:

• This position will be Fully Onsite and require 4+ days in the Cambridge office per week.
• The ideal candidate is a 3rd/4th-year undergraduate student or graduate student with a background in organic chemistry, analytical chemistry, informatics, or chemistry-related program.
• Completion of the following classes is required:
  • General Chemistry 1 +2 including Lab
  • Organic Chemistry 1+2 including Lab
  • Instrumental Methods of Analysis
  • Completion of the following classes is recommended:
  • Physical Chemistry 1
  • Spectroscopy of Organic Compounds
• A deep understanding of organic mechanisms is a plus.
• Desired Lab Skills:
  • Practical familiarity with common analytical techniques (HPLC, LC-MS, and NMR) is required.
  • The motivation to apply analytical instrumentation to solve cutting-edge research problems in structural characterization would be beneficial.
  • This position requires good organizational and communication skills, attention to detail, and the ability to function effectively as a team member.
• Basic understanding of computer skills including MS Office (PowerPoint, Words, Excel)
• Internet skills including use of e-mails, group messaging and information gathering
• Highly reliable and a strong team player
• Flexible with an attention to detail
• Strong verbal and written communication skills

Internship Eligibility

• Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship
• Must be currently enrolled in a degree program graduating December 2025 or later
• The internship program is 10-12 weeks depending on the two start dates(June 2nd- August 22nd)or(June 16th -August 29th)
  • The intern must be able to commit to one of these time frames
• Able to work full time 40 hours a week during internship dates
• Takeda does not provide a housing stipend or relocation support for the U.S Summer Internship Program

 Program Highlights:

• Hands-on experience with real projects and responsibilities
• Dedicated mentorship program pairing interns with experienced professionals
• Networking opportunities with industry professionals and fellow interns
• Internship events focused on professional and skills development
• Exposure to multiple business areas or departments within a Pharmaceutical Organization

Applications will be accepted between December 18th and January 10th

For Location:

U.S. Hourly Wage Range:

$21.00 - $46.00

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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Job Exempt