Sensor Technologies Engineer
Boston, Massachusetts- Job Level: Senior
- Travel: 5-10%
The Pharmaceutical Sciences (Pharm Sci) organization is an integral part of global R&D at Takeda, translating science into therapeutic products for patients. When you join Pharm Sci, you become part of a team dedicated to bringing our products to life for our patients through innovation, dedication and talent while minimizing environmental impact.
We work as a member of Takeda’s Global Program Team (GPT) and take full ownership of Chemistry, Manufacturing & Control (CMC) activities — driving product development from bench to bedside.
The Pharm Sci team focuses on executing and enhancing business processes and partnering with key stakeholders and industry leaders to boldly deliver an increasingly complex portfolio. Always looking through a sustainability lens to protect our planet, we are embracing new ways of working, excelling in our data and digital transformation, building differentiated capabilities (CMC Acceleration), delivering innovative medical devices, and advancing an inclusive, innovative culture.
It is an exciting time to be in Pharm Sci. Join our journey and change the lives of patients!
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Job Description
Objective:
Synthetic Molecule Process Development (SMPD) is responsible for the development of robust and cost-effective processes for the manufacture of new small molecule pharmaceuticals, along with methods for achieving and controlling high standards of purity and quality.
The Staff Engineer – Advanced Sensor Technologies will be joining a vibrant and innovative group of engineers and scientists, responsible for:
Designing, building and implementing sensor technologies to solve existing and emerging measurement requirements for ongoing and planned processes
Working with project teams to interface with manufacturing and drive the implementation of PAT to realize a paradigm shift to data rich manufacturing and enabling automation
Serving as a subject matter expert on interdisciplinary departmental and cross-functional workstreams and work to democratize PAT across the global SMPD function
Staying current on emerging trends, new technologies, and external communities & consortia related to, e.g., novel metrology techniques - particularly for liquid and powders
Accountabilities:
Assists in the development of end-to-end control strategies & systems for drug substance synthetic molecule continuous manufacturing processes.
Works with cross-functional and/or external partners to develop and deploy next generation sensor solutions.
Develops a modular plug & play sensor architecture.
Independently designs and executes experiments for validation of novel sensor technologies.
Partners with Automation, Manufacturing, Process Engineers & PAT experts to develop metrology solutions that are deployable across the global organization for the measurement and/or detection of quantities of interest in drug substance manufacturing.
Enables automation technology projects with the development and application of appropriate measurement solutions.
Assists with the development of project strategy and communicates complex technologies within the department and cross functionally as necessary.
Builds and maintains relationships with key vendors and assists with technical aspects of vendor negotiations.
Responsible for authoring relevant sections of regulatory documents, reports and peer reviewed manuscripts.
Proactively analyses technical issues and coordinates potential resolution with team members.
Education, Experience, and Skills:
Required:
Bachelors degree in Physics, Chemometrics, Chemical or Electrical Engineering or related pharmaceutical science and 8+ years relevant industry experience
Masters degree in Physics, Chemometrics, Chemical Engineering or related pharmaceutical science 6+ years relevant industry experience
PhD in Physics, Chemical Engineering or related pharmaceutical science and 0+ years relevant industry experience
Strong knowledge and understanding of optical and electronic metrology techniques
Experience with industrial communication protocols such as Ethernet/IP, Profibus, Modbus, OPCUA etc.
Experienced with communicating and data collection from systems such as sensors, controllers, and industrial systems
Good knowledge of the state of the art in existing PAT a plus
Experience with Matlab/Python/R/SQL a plus
Experience in multivariate analysis and/or statistical and/or mechanistic and/or deep learning methodologies a plus
Understanding of synthetic molecule process development activities a plus
Understanding of current Good Manufacturing Practices (cGMP) a plus
Knowledge and Skills:
Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions
Teamwork - Ability to work well in highly cross functional team environment and across global line functions
Communication Skills -Able to expresses one’s self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates issues to supervisor; technical writing skills to support authorship of internal technical documents
Organization - Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously
Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use
Resource Management - Ability to manage one’s time within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors)
External Involvement - Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events
Technical - Subject matter expertise and knowledge of applicable lab equipment and operations
Travel Requirements:
May require approximately 5-10% travel
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Boston, MAU.S. Base Salary Range:
$108,500.00 - $170,500.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
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