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Job Description

About the Role:

• Drive value demonstration strategies for Health Technology Appraisal (HTA; including the EU Joint Clinical Assessment [JCA]) and payer assessments to optimize rapid, broad patient access, achieve value-based prices and lead performance in line with commercial objectives

• Lead health economics (HE) plans and outline strategic approaches to drive pricing and reimbursement activities. Drive hands-on economic assessments for oncology medicines at all stages of development, using HE models and materials including systematic literature reviews (SLRs), indirect treatment comparisons (ITCs), statistical analyses of trial and real-world data and other methods as appropriate

• Oversee country roll-out and training on global HE materials and provide country response to payer inquiries. Lead the development and country adaptations of HTA models with regional and local operating company (LOC) Market Access and HE leads

• Lead and develop robust publication plans to drive access to portfolio medicines through HTA assessments and life cycle management

How you will contribute:

Global Value Proposition:

• Establish a comprehensive understanding of the burden of disease(s), unmet need and appropriate comparator

• Co-lead with Market Access the development of the global value proposition to ensure a compelling value story for payers

• Identify and prioritize strategic opportunities to enhance and expand product value proposition for new indications

Evidence Generation:

• Drive evidence generation planning to optimally provide the product clinical, economic and humanistic value to HTA bodies, payers and market access decision makers and lead the coordination across functions to ensure evidence needs are incorporated into Global, Regional and Local initiatives

• Thoroughly evaluate the anticipated outcome of HTA body assessments and the implications for value positioning and evidence requirements, and shape the product’s evidence generation plan

• Make recommendations to cross-functional business partners about the need for additional data generation – clinical trial, real world evidence (RWE) such as registries and databases – based on evidentiary requirement of payers and HTA bodies

• Lead the integration of payer-relevant HE endpoints in the clinical development plan

HE and Value & Access Tools

• Lead the development of state of the art HE models and studies (e.g., SLRs, ITCs) with sufficient evidentiary support to withstand critique of HTA bodies and other key access decision makers

• Lead training to Regions and LOCs on product value platforms, new evidence and HE studies and models

• Co-lead with Pricing & Market Access the conceptualization of value-based contract (VBC) options, develop VBC toolkits, and assess their commercial impact and effect on cost-effectiveness and budgetary impact

• Support the development/updating and review of the product value platform (including but not limited to Value Story, Global Value Dossiers, Objection Handler, Access Solutions Toolkit and Global Pricing Guidance)

Market Access:

• As the expert on the product’s value proposition and evidence package, this role will proactively address brand-related payer, HTA and policymaker demands and respond to emerging or unforeseen market opportunities/challenges in close coordination with the regional/local PVA Leads

• Maintain awareness of the quickly evolving Global HTA and reimbursement landscape and the evidentiary needs of health care decision-makers to guide HE strategies

Communication/Publication:

• Ensure the drug’s value proposition will be recognized among the external (scientific/ payer influencing/HTA expert) stakeholder community and hence market access and market uptake will be maximized

• Communicate and translate HE messages effectively in manuscripts, posters and publications, and develop appropriate communication materials and tools for payers and population healthcare decision makers

Foster Superior Collaboration:

• Foster productive collaboration and effectively manage several important partnerships and consultants, to achieve impact and contribute to the company’s success.  These interfaces include but are not limited to Global Brand Teams (GBTs), Global Product Team (GPTs), Regional and Local Market Access leads, US & Japan Payer Marketing and Market Access, Global Evidence and Outcomes, Medica Affairs, Clinical Development, Regulatory Affairs, Biostatistics, Global Emerging Markets (GEM; e.g., China), Project Leadership, Finance, Corporate Communications and Business Development

• Develop and manage strong collaborations with HE key opinion leaders, academic researchers and vendors to ensure excellence in HE activities and being up to date on the latest and most innovative HE methods

CORE ELEMENTS RELATED TO THIS ROLE.

• Lead Role of Takeda Oncology HE projects accountable to Head, Global Health Economics & US HEOR

• Scope to lead and partner with all LOCs globally in value demonstration and HTA via HE modelling and relevant studies (e.g., SLRs, ITCs, RWE)

• Remit includes all in-market brands and development molecules

DIMENSIONS AND ASPECTS

Leadership

• Ability to work cross functionally and cross regionally to lead and partner all LOCs; indirect leadership at LOC level

Decision-making and Autonomy

• Responsibility in line with Associate Director level position; independently lead HE projects and support the Global Health Economics Center of Excellence internal and external initiatives and activities

Interaction

• Market Access, Pricing, Advocacy, Biostatistics, Global Evidence and Outcomes, Medical Affairs, Clinical Science, Legal, Regulatory

• OBU 10, EUCAN, GEM

Minimum Qualifications/Requirements:

• Doctorate with 4+ years of experience, Master's with 6+ years of experience or Bachelor's with 8+ years of experience in healthcare industry with direct experience in global product value proposition development (industry or consulting) and interaction with payers, HTA bodies, relevant policymakers and strong patient-centered focus

• Robust understanding of the global payer environment and in-depth understanding of ex-US payer landscape including HTA trends and guidance (e.g., NICE, CADTH, PBAC, EU JCA) along with knowledge of US Medicare (Part D), ICER in the US and trends in Emerging Markets (e.g., China) – including reimbursement methodologies, pricing/reimbursement authorities’ decision-making process and current reimbursement issues

• Strong knowledge and hands on experience in health economics, health technology assessment (HTA) tools, methods and filings, SLRs, ITCs, statistical analyses and economic modelling

• Knowledge and understanding of clinical and epidemiological information, innovative global pricing models, all phases of drug development methods of analysis of large databases (e.g., claims data, electronic health records) and the major areas of Outcomes Research (PROs, modelling)

• Leadership – strong ability/desire to work in a highly matrixed organization

• Strong analytical capabilities and excellent communication skills (written and oral)

• Strategic thinking and demonstrated problem solving capability

• Influencing skills (one on one and in group setting) – consensus builder with ability to effective drive decision making

• Ability to translate technical issues to non-technical experts

Preferred:

• Previous experience in Hematology and/or Oncology

• A combination of Global and US, in-depth knowledge of HTA (including EU JCA) requirements and direct experience in HTA submissions

• Direct payer experience and/or experience in Market Access

• Track record of peer-reviewed publications

Travel Requirements:

• 5 to 10% Domestic and/or International travel may be required

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$153,600.00 - $241,340.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.