Associate Scientific Director, GI Inflammation Biomarker Discovery ResearchSan Diego, California
- Job Type: Full Time
- Job Level: Senior
- Travel: Minimal (if any)
At Takeda, we strive to provide transformational opportunities for every member of our team, and we empower our people to take charge of their futures. In an environment that fosters lifelong learning and a growth mindset, you’ll have the support you need to thrive — at work and beyond.
About the role:
At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
Join Takeda as an Associate Scientific Director where you will lead a small team of scientists to design preclinical target engagement and pharmacodynamic assays and analysis of biomarkers in various animal/in vitro models. You will also lead the development and implementation of a defined strategy for preclinical biomarker development that will provide data to support goals/strategy of the early clinical development team. As part of the Inflammatory Disease Research team you will report to the Senior Director and Head Celiac Discovery and have a deep knowledge of inflammatory diseases (e.g. IBD), fibrosis and preclinical biomarker development/utility in various disease indications.
How you will contribute:
Leads the development of preclinical biomarker strategy, working closely with preclinical pharmacology, DMPK and clinical translational groups to develop integrated translational plans.
Lead teams in efficient and effective design/validation of well-defined and controlled methods to measure pharmacodynamic (PD), target engagement (TE) and disease specific biomarkers in preclinical models.
Experience in assay technologies including (but not limited to): MSD, ELISA, qPCR, flow cytometry and other technologies used for biomarker development.
Expected to develop (and help direct reports develop) and meet goals/timelines/budgets for project teams.
BS with 15+ years research experience, or MS with 13+ years research or PhD with 7+ years of experience. Experience in a scientific discipline of cellular & molecular biology, immunology, or equivalent.
Outstanding expertise in autoimmune disease/IBD and biomarker development.
Communicates and collaborates with colleagues and management effectively.
Up-to-date knowledge of in current scientific advancements in new biomarker technologies and competitive landscape of given indications.
Guide the design, optimization, and execution of well-controlled protocols to support biomarkers in preclinical projects with the ability to troubleshoot as needed.
Extensive experience in the analysis and interpretation of data from ligand binding assays, flow cytometry and molecular techniques.
Previous experience in biomarker assay development and validation is required.
Deep understanding of preclinical models of autoimmune disease and/or IBD pathogenesis.
What Takeda can offer you:
Comprehensive Healthcare: Medical, Dental, and Vision
Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
Community Outreach Programs and company match of charitable contributions
Family Planning Support
Flexible Ways of Working
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Base Salary Range: $137,200 to $196,000, based on candidate professional experience level. Employees may also be eligible for Short-term and Long-Term Incentive benefits as well. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off. The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.
In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
LocationsSan Diego, CA
Time TypeFull time
Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.
Working at Takeda
InclusionHere, you will feel welcomed, respected, and valued as a vital contributor to our global team.
CollaborationA strong, borderless team, we strive together towards our priorities and inspiring mission.
InnovationBold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
Top WorkplaceRecognized for our culture and way of working, we’re one of only 15 companies to receive Top Global Employer® status for 2023.
Work-LifeOur people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
EmpowermentThrough trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.
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