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Analytical Development, Cell Therapies PhD Internship - Summer 2024

Cambridge, Massachusetts
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  • Job Type: Full Time
  • Job Level: Senior
  • Travel: Minimal (if any)

At Takeda, we strive to provide transformational opportunities for every member of our team, and we empower our people to take charge of their futures. In an environment that fosters lifelong learning and a growth mindset, you’ll have the support you need to thrive — at work and beyond.

Job ID R0111427 Date posted 12/04/2023 Location Cambridge, Massachusetts

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’sPrivacy Noticeand Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we strive to create an exceptional people experience for patients, communities, partners, and employees. As a patient-focused, values-based, R&D-driven global biopharmaceutical company, we know our decisions and actions affect people’s lives. We look to our values of Takeda-ism, which incorporates Integrity, Fairness, Honesty and Perseverance, and Patient-Trust-Reputation-Business as a guide in our decision-making process to ensure we do what’s right – for our patients, our people and society.

Are you ready to embark on a transformative journey with Takeda? Our paid 10–12-week summer internship program is designed to immerse you in a dynamic learning environment, featuring a blend of developmental and social activities.

As a Takeda intern, you'll have the opportunity to contribute to impactful projects that play a crucial role in shaping both our business and the well-being of patients. This experience will not only allow you to apply your technical and business knowledge but also empower you to showcase your analytical strength and creative problem-solving skills.

Seize this chance to gain hands-on experience, expand your skill set, and make a meaningful impact on the healthcare industry. We invite you to be a part of our innovative and collaborative team, where your contributions matter.

For more information about Takeda, please visit www.takeda.com. op of Form

Please note that Takeda does not provide intern housing or a housing stipend.

Project Outline:

The goal of this project is to optimize and validate next-generation sequencing (NGS) based assays for the detection of potential adventitious agents in cell banks, cell drug products, and viral vectors.

Adventitious agents are unwanted or unintended biological agents, such as viruses, that may contaminate cell cultures or final cell therapy products during the manufacturing process. Detecting these agents is crucial for ensuring the safety and quality of cell therapy products. NGS technology, known for its high-throughput and high-resolution sequencing capabilities, allows for comprehensive and sensitive detection of a broad range of adventitious agents within a single assay. Incorporating NGS-based adventitious agent testing into the development and manufacturing processes of cell therapy drug products can significantly enhance safety, quality control, and compliance with regulatory standards, ultimately contributing to the successful translation of these therapies from the laboratory to clinical application.

The intern will be responsible for supporting the assay development, conducting experiments, analyzing data, and assisting in the overall qualification process and work onsite (Cambridge, MA) The project aims to enhance the safety and quality control of cell drug products through robust adventitious agent testing using NGS technology.

How you will contribute:

  • Work closely with other team members to optimize and validate NGS-based assays for adventitious agent testing in cell therapy samples.

  • Participate in assay development, including protocol design, reagent preparation, and optimization of sequencing parameters.

  • Assist in the preparation and processing of cell therapy samples for NGS-based adventitious agent testing.

  • Perform data analysis using bioinformatics tools to identify potential adventitious agents and assess the quality of sequencing data.

  • Maintain detailed and accurate records of experiments, protocols, and results.

  • Summarize findings in regular reports and presentations for internal team meetings.

  • Contribute to the implementation of quality control measures to ensure assay reproducibility and accuracy.

  • Work on troubleshooting and resolving technical issues related to assay performance.

  • Collaborate with cross-functional teams to integrate assay results into broader cell therapy programs.

  • Exceptional interpersonal, verbal communication and writing skills.

  • Deadline-driven with an elevated level of organizational and planning skills.

  • Strong quantitative, analytical, problem solving and conceptual skills.

  • Proven record of accomplishment of teamwork, adaptability, innovation, initiative, and integrity.

  • Global mindset to grow in a diverse work environment.

Requirements / Qualifications:

  • Currently authorized to work in the United States without sponsorship. Takeda does not provide sponsorship for internship positions.

  • Available to work full-time (40 hours per week), within the core business hours of 8:00am – 5:00pm, for 10-12 weeks during the summer months.

  • PhD, MD student with completion of a minimum of one year of university studies.

  • Must be enrolled in school the semester following your internship with Takeda.

  • Please note that Takeda does not provide intern housing or a housing stipend.

The hourly pay rate range is $20.00 per hour - $46.00 per hour. The final pay rate offered for this internship may consider several factors including, but not limited to, location, skills, education, and experience.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Cambridge, MA

Worker Type

Employee

Worker Sub-Type

Paid Intern (Fixed Term) (Trainee)

Time Type

Full time
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Where you fit in

Our team at Takeda is tackling some of the most challenging problems in drug discovery and development. As the newest member of our Research team, you’ll conduct purposeful, meaningful work on groundbreaking modalities that may lead to breakthrough drugs.

With our deep investment in next-generation technologies, you’ll have the resources and support to do your best work. As a part of our team, you’ll connect with brilliant minds inside and outside of Takeda. We are committed to collaborating with academia and emerging biotech companies to expand our reach and impact in cell therapy, gene therapy and data sciences.

Our team’s wide-ranging expertise includes medicinal chemistry, genomics datasets, immunofluorescence, high content imaging, flow cytometry, transcriptional profiling, multi-step synthesis, multimodal genetics, pharmacokinetics and much more. Whatever area inspires you, your work will support the progression of an innovative, industry-leading discovery pipeline and make an impact that matters to patients and society.

A career in Research at Takeda will give you everything you need to succeed professionally — and make a difference to patients, people and the planet.

  • Design and carry out experiments

  • Manage multiple projects

  • Document data

  • Mentor other scientists

I feel especially lucky to be able to work with colleagues across the industry to meet a unified goal.Takeda is paving the way for how research will be conducted in the future.

Daniel Scheibe - Senior Manager Operations, Systems Engineering, Drug Discovery Sciences

Along with incredibly passionate colleagues, there’s a clear commitment to invest in the best facilities and the right equipment needed to successfully perform world-class science.

Christina Alves - Head of Biotherapeutics Process Development

Our pipeline

Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.

Learn more

What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

Exterior of Takeda Building

About our location

Cambridge, Massachusetts


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