Skip to main content
three employees in a lab looking at something through a microscope

Director, Oncology R&D Strategy and Portfolio Management

Boston, Massachusetts
Apply Now
  • Pay Range: $169,400.00 - $266,200.00
  • Job Level: Senior
  • Travel: Minimal (if any)

Takeda has been translating science into breakthrough medicines for 240 years. Every step of the way, our teams have worked together to tackle some of the most challenging problems in drug discovery and development. Today, we’re a driving force behind innovative therapies that make a lasting difference to millions of patients around the world.

In R&D, all of our history and potential comes together in an environment that welcomes diversity of thought and amplifies every voice. Working closely with colleagues, you’ll play a key role in bringing our rich pipeline of products forward to help patients. Come join a team that’s earned trust for more than two centuries, and find out how advancing transformative therapies at Takeda will shape your bright future.

Job ID R0119359 Date posted 04/10/2024 Location Boston, Massachusetts Pay Range $169,400.00 - $266,200.00

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’sPrivacy Noticeand Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.


Partner in the development and drive the execution of an integrated Oncology R&D strategy that facilitates efficient drug development across all phases of development and seamlessly supports business needs. As a core member of the OTAU Strategy and Operations leadership team, the Lead, OTAU R&D Strategy and Portfolio Management serves as a key partner to the OTAU Strategy & Operation Head and the OTAU LT and helps ensure agile execution of the Oncology R&D portfolio strategy. This role drives portfolio analyses needed for effective decision making and ensures clear communication of portfolio strategy, status and decisions across the One Oncology organization.  The role will regularly interact with and help facilitate meetings of senior governance bodies across the One Oncology organization, including the Takeda Oncology Management Meeting (TOMM) and the Oncology Development Strategy Team (ODeST).


Portfolio Strategy and Management - Strategic Initiatives - Portfolio Modelling & Analytics

  • Works closely with the Head of OTAU Strategy and Operations and the OTAU LT to help drive the development, communication and continuous refinement of an end-to-end, integrated R&D Oncology TAU strategic framework.  The framework will encompass early and late-stage assets and be aligned with Disease Area Strategies to enable portfolio-level decision-making.
  • Works closely with senior Oncology Leadership across OTAU, ODDU and OBU to define a near and long-term OneOncology portfolio vision.  This includes an external oncology strategy vision focused on key assets and technology platforms in close collaboration with Global Business Development and the Center for External Innovation.
  • Actively contributes to real-time and effective portfolio prioritization, decision making and key portfolio analytics to support individual asset and portfolio-level decision making.  This includes strategic context setting, decision structuring, risk assessments, value profiles, PTRS development in conjunction with GPTs, PRC, TOMM and ODeST preparations, etc.
  • Provides strategic input and drug development expertise to Oncology management reviews, including quantitative scenario development, trade-off implications and the assessment of investment opportunities. Monitors portfolio progress, identifies trends, risks and gaps, and recommends specific strategies to optimize Takeda’s oncology portfolio under the supervision of the Head of OTAU Strategy and Operations.
    • In close coordination with relevant stakeholders across the One Oncology organization, provides portfolio insights in support of corporate planning cycles, e.g. IR earnings calls, MRP, LRF, etc.
  • Ensure TOMM and ODeST governance agendas and meetings are managed appropriately, resulting in focused, agenda driven meetings, and effective decision making.  Strives for continuous improvement in decision making approaches and communicates and monitors governance recommendations and decisions.
  • Leads strategic initiatives under the direction of the Head of OTAU Strategy and Operations to improve the portfolio management, portfolio linkage and prioritization methodology, as well as develops mechanisms to effectively respond to internal strategic imperatives and evolving business needs.
  • Helps facilitates the Oncology Advisory Board, including compilation of Board feedback and implementation of Board recommendations.
    • Represents the OTAU portfolio planning and strategy function to internal and external stakeholders.



  • Advanced scientific degree (PhD, MD, or MBA)
  • Minimum of 5-7 years of relevant experience in the biopharmaceutical, biotechnology or life science consulting industry, with in-depth knowledge of research and development and related commercial operations.
  • Minimum of 5 years of drug development experience in the biopharmaceutical/biotechnology industry with interdisciplinary global experience with complex projects, such as program leadership, strategy and execution, insights and analytics, etc.
  • Ability to synthesize information from multiple sources, communicate ideas and data both verbally and written in a persuasive and appropriate manner in a matrix environment.
  • Experience presenting to, and interacting with, Senior Executives in R&D and Business organizations in R&D-driven multinational biopharmaceutical or large biotechnology organizations.
  • Ability to drive and influence decision-making across all levels of the organization.
  • Displays a firm grasp of modern decision analytics approaches.

Knowledge and Skills:

  • Unwavering commitment to patients ensuring that their decisions and actions are guided first and foremost by what is best for patients.
  • A goal directed high achiever who embraces calculated risks and clear steps to discharging risk.
  • A leadership approach where results have been achieved through developing high performance in others and who is passionate about developing others into future leaders.
  • An agile learner who consistently enables leadership to make high quality decisions that deliver differentiated medicines to patients in need.
  • An organizationally savvy systems thinker who can identify and address impediments to high performance in a work system, evolving the organization to produce envisioned results.
  • A thoughtful thinker who can translate strategy into applied business approaches to ensure the organization will be successful in the near and long-term.


  • Willingness to travel, including overnight trips. Some international travel may be required.
  • Requires approximately 5-10% travel.



Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$169,400.00 - $266,200.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


Boston, MA

Worker Type


Worker Sub-Type


Time Type

Full time
Apply Now
During my 20-year journey here, I’ve been fully supported by my colleagues, and I can’t say enough about our rich internal talent and the long-standing values that drive our decisions as we work to develop important medicines for the patients we serve.

Doug Coffman - Head, R&D Asset Transition & Integration Office, R&D Regional & Business Operations

When making any type of decision, the first thing we ask is 'how will this impact patients?’ Ultimately, we’re laser focused on the best interests of the patient, and I truly believe we follow through on that.

Meredith Culp - GPM Head & Chief of Staff, Neuroscience Therapeutic Area

Our culture and shared values make us like a family here at Takeda. It doesn't feel like work when you're doing something you love with people you love, and when your outcome is really fantastic.

Alison Handley, Head, Center for External Innovation

The heart of our work

Shining a light on new perspectives

What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.


Create an exceptional people experience.


Protect our planet.

Data & Digital

Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

Exterior of Takeda Building

About our location

Boston, Massachusetts

View Map of Boston, Massachusetts

Join our talent community

Get customized job alerts sent right to your inbox. Plus, get the latest in company news and other important resources by signing up for our talent community.

Learn about job updates